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Comparison of FLIXENE™ and standard PTFE arteriovenous graft for early haemodialysis

Abstract

ABSTRACT

Purpose: The purpose is to compare the outcomes of FLIXENE™ arteriovenous graft (AVG) to standard polytetrafluoroethylene (PTFE) AVG for early haemodialysis.

Methods: This is a prospective observational study of all AVGs placed over a 40-month period between 2008 and 2011 at our vascular unit. Primary outcome was to examine early cannulation rates for FLIXENE™. Secondary outcomes included patency rates, usability of grafts, complications in particular infections, interventions and death in comparison to standard PTFE grafts.

Results: Forty-five FLIXENE™ and 19 standard PTFE AVGs were placed in the study period; 89% of FLIXENE™ grafts were used for dialysis, with 78% cannulated within 3 days. At 18 months, primary patency (FLIXENE™ 34% vs standard PTFE 24%), primary assisted patency (35% vs 36%) and secondary patency rate (51% vs 48%) were not statistically different; 20.2% of FLIXENE™ grafts were infected at 18 months requiring explantation compared with 40.3% of standard PTFE grafts (p=0.14).

Conclusions: FLIXENE™ can be cannulated for dialysis within 3 days. It has similar patency and complication rates as other prosthetic grafts in the market. In patients who have no access and require urgent dialysis, FLIXENE™ is a viable option.

J Vasc Access 2014; 15(2): 116 - 122

Article Type: ORIGINAL RESEARCH ARTICLE

Article Subject: Dialysis

DOI:10.5301/jva.5000213

Authors

Nathaniel Chiang, Katherine Ria Hulme, Paul Charles Haggart, Thodur Vasudevan

Article History

Disclosures

Financial support: No competing interests or financial support declared.
Conflict of interest: None.

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Authors

Affiliations

  • Waikato Hospital, Hamilton - New Zealand

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